ORGN: Division of Organic Chemistry

523 – Regioselective C–N bond formation via gold catalysis

Louis Marchetti¹ , Abhishek Kantak¹ , Riley Davis¹ , h_davis@my.uri.edu, Brenton DeBoef^1
1 University of Rhode Island, Kingston, Rhode Island, United States

Abstract:This poster presents a novel protocol for the intermolecular, regioselective amination of arenes. A direct and novel route for regioselectively accessing various substituted aniline compounds has been achieved through the use of an Iodine (III) oxidant in the presence of a Gold (I) catalyst. Yields as high as 90% were recorded. Regioselectivity can be predicted based on electrophilic aromatic metalation patterns.

ORGN: Division of Organic Chemistry

477 – Binding analysis of Xe-129 with cyclotriveratrylenes (CTV) compounds

John Rhoat¹ , john.rhoat008@gmail.com
¹ Chemistry, University Of Rhode Island, Kingston, Rhode Island, United States

Abstract:An amino functionalized cyclotriveratrylene (CTV), a bowl-shaped molecule, was recently shown to reversibly bind Xe-129 through unique chemical shift in the ¹²⁹Xe NMR spectrum. The nature of the host guest relationship between the amine CTV and the Xe-129 is largely unknown. To explore this relationship and investigate the hypothesis of hydrogen bonding around Xe-129 to form a cryptophane like cage, the substituents around the rim of the bowl were varied. Several synthesized derivatives were tested in their ability to bind Xe-129.